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Disease-relevant β2-microglobulin variants share a common amyloid fold.
Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA. Wilkinson M, et al. Among authors: aubrey ld. Nat Commun. 2023 Mar 2;14(1):1190. doi: 10.1038/s41467-023-36791-8. Nat Commun. 2023. PMID: 36864041 Free PMC article.
Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure.
Konstantoulea K, Guerreiro P, Ramakers M, Louros N, Aubrey LD, Houben B, Michiels E, De Vleeschouwer M, Lampi Y, Ribeiro LF, de Wit J, Xue WF, Schymkowitz J, Rousseau F. Konstantoulea K, et al. Among authors: aubrey ld. EMBO J. 2022 Dec 17;41(2):e108591. doi: 10.15252/embj.2021108591. Epub 2021 Nov 29. EMBO J. 2022. PMID: 34842295 Free PMC article.
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid.
Aubrey LD, Ninkina N, Ulamec SM, Abramycheva NY, Vasili E, Devine OM, Wilkinson M, Mackinnon E, Limorenko G, Walko M, Muwanga S, Amadio L, Peters OM, Illarioshkin SN, Outeiro TF, Ranson NA, Brockwell DJ, Buchman VL, Radford SE. Aubrey LD, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2309700120. doi: 10.1073/pnas.2309700120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170745 Free PMC article.